Otud6a c-myc

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WebFeb 1, 2024 · Cancer stem cells (CSCs) play significant roles in cancer development, drug resistance and cancer recurrence. In cancer treatments based on the CSC characteristics … WebCROSS-REFERENCE TO RELATED APPLICATIONS. This application is a Continuation of U.S. patent application Ser. No. 16/649,732, filed Mar. 23, 2024, which is a national stage filing u

OTUD6A promotes prostate tumorigenesis via deubiquitinating

WebFigure 3. OTUD6A interacts with Aurora-A through the OTU and kinase domains, respectively. (a) SFB-tagged OTUD1 and OTUD6A were transfected into HEK293T cells, … WebSep 7, 2024 · Ovarian tumor deubiquitinase 6A (OTUD6A) was previously reported as a downregulated DUB in HCT116 cells with p53 knockdown. Therefore, it was expected that … breztri monographie

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WebJan 11, 2024 · Cargnello M, Topisirovic I (2024) c-Myc steers translation in lymphoma. J Exp Med 216: 1471 – 1473 Crossref CAS PubMed Web of Science® Google Scholar; Carroll … WebMar 1, 2024 · OTUD6A stabilizes Brg1 and AR a IB analysis of VCaP cells infected with the indicated lentivirus for 48 h. b IB analysis of VCaP and 293T cells transfected with the … WebPOU5F1/OCT4, SOX2, MYC/c-Myc and KLF4 are the four Yamanaka factors. When combined, these factors are sufficient to reprogram differentiated cells to an embryonic … tamil new dj remix kuthu songs

OTUD6A Is an Aurora Kinase A-Specific Deubiquitinase - MDPI

Prostate-specific oncogene OTUD6A promotes ... - nature.com

WebMar 21, 2024 · OTUD6A (OTU Deubiquitinase 6A) is a Protein Coding gene. Diseases associated with OTUD6A include Junctional Epidermolysis Bullosa Non-Herlitz Type . … WebMar 1, 2024 · Furthermore, the interaction of OTUD6A with Brg1 and AR was also verified in other prostate cancer cell lines, including PC-3, LNCaP, and C4-2 cells, through IP-IB … breztri product monograph canadaWebFeb 28, 2024 · 这项研究发现去泛素化酶家族成员OTUD6A是前列腺中特有的c-Myc去泛素化酶，其高表达是促进前列腺癌发生的重要原因。c-Myc是一种不稳定的蛋白质，通过E3连 … breztri 10.7 grams

"WebBased on this result, OTUD6A was chosen as a final candidate DUB and subjected to the subsequent experiments. Int. J. Mol. Sci. 2024, 22, x FOR PEER REVIEW 4 of 13 Figure 2. … " - Otud6a c-myc

Otud6a c-myc

WebFeb 25, 2024 · Cell Death & Differentiation, Published online: 25 February 2024; doi:10.1038/s41418-022-00960-xProstate-specific oncogene OTUD6A promotes prostatic … WebFeb 25, 2024 · Compared with the wild type OTUD6A (OTUD6A-WT), OTUD6A-C152A mutant was incapable of deubiquitinating c-Myc (Fig. 2E), supporting the notion that OTUD6A is …

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WebAbout Press Copyright Contact us Creators Advertise Developers Terms Privacy Policy & Safety How YouTube works Test new features NFL Sunday Ticket Press Copyright ... WebOct 17, 2024 · OTUD6A interacts with Drp1. (A) Drp1 specifically interacts with OTUD6A in cells. IB analysis of IP and WCL derived from HEK293 cells transfected with HA-Drp1 and …

WebAnti-Myc Tag Antibody, clone 4A6 Anti-Myc Tag, clone 4A6, is a mouse monoclonal antibody that is validated for use in ChIP, IC, IF, IP, and WB for the detection of Myc Tag and does … WebJan 1, 2024 · Europe PMC is an archive of life sciences journal literature.

WebMar 21, 2024 · An important paralog of this gene is OTUD6A. UniProtKB/Swiss-Prot Summary for OTUD6B Gene [Isoform 1]: ... Influences the expression of CCND1/cyclin D1 … WebEfficacy of antisense morpholino oligomer targeted to c-myc in prostate cancer xenograft murine model and a Phase I safety study in humans. Clin Cancer Res. 2003;9(7): 2510-9. …

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WebFeb 1, 2024 · These results indicate that OTUD6A is a physiological DUB for c-Myc in PrCa setting and specifically promotes prostatic tumorigenesis through stabilizing c-Myc … tamil news jothidamWebJan 16, 2024 · (c) Schematic representation of full-length (FL) and truncated mutants of Aurora-A. (d) SFB-tagged OTUD6A was co-transfected with MYC-tagged full length or … tamil nicknamesWebCorresponding OTUD6A RNA-seq data are presented for the same tissues. Show all images [1 pictures] Western blot analysis in control (vector only transfected HEK293T lysate) and … tamil news 7 kalivi neram latestWebThe proteasome is a complex molecular machine degrades proteins after they are bound to ubiquitin. 18 Ubiquitin can be degraded by proteasome via its conjugated substrate when extended with a C-terminal tail and as a monomer. 19 Furthermore, disorders of ubiquitination and deubiquitination can lead to various diseases. 20 Masclef et al. … tamilnilam loginWebApr 10, 2024 · Moreover, only OTUD6B but no other OTU family members was able to regulate β-TrCP, since knock down OTUD6A or OTUD2 did not increase β-TrCP protein … tamil nicknameWebMar 5, 2024 · Full-length p53 cDNA was subcloned into pcDNA3-HA vector from a pcDNA3-Myc-p53 vector used in our previous ... (B and C) The mRNA expression levels of (B) USP5 … tamil new videos songsWebOTUD6A Protein LS-G94057 is an Over-Expression Lysate Human OTUD6A with Myc-DDK (Flag) tag(s). Products. Research Areas. COVID-19. Resources. Contact Us. Distributors … breztri product monograph